NFL Week 6 Same Game Parlay: San Francisco 49ers vs. Cleveland Browns

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The much-anticipated showdown between the San Francisco 49ers and the Cleveland Browns in NFL Week 6 has lost some of its competitive luster due to the Browns’ ongoing issues. The 49ers, boasting a flawless 5-0 record and the coveted #1 spot in the Pickswise NFL Power Rankings, will be determined to continue their winning streak. In contrast, the Browns, fresh from their bye week, are grappling with internal crises. Nevertheless, the stage is set for an exciting matchup in Ohio, and we’ve assembled a 3-leg Same Game Parlay with the potential for a significant payout at +1013 odds from FanDuel Sportsbook.

NFL Week 6 Picks and Same Game Parlay: 49ers Aim to Maintain Perfect Record in Clash with Struggling Browns

While you can explore the complete game preview in our Week 6 NFL picks, let’s delve into our 49ers vs. Browns Same Game Parlay.

NFL Pick: 49ers -9.5 (-108)

The 49ers have launched the season with unwavering dominance, securing their initial five victories by margins of 23, 7, 18, 19, and 32 points. A victory margin of just 10 points is needed to initiate our parlay with a successful leg. While this may have posed a challenge if the Browns were operating at full capacity (as evidenced by the initial 3-point favoring of the 49ers), it’s difficult to envision the current state of the Browns leading to a closely contested affair.

The Browns, with a 2-2 record, are poised to field their third starting quarterback in only their fifth game. Rookie Dorian Thompson-Robinson endured a challenging baptism by fire against the Ravens when he found out on the morning of the game that starter Deshaun Watson would be sidelined due to a shoulder injury. The outcome, a 28-3 loss, reflected the circumstances. With Watson’s health still uncertain after a week of rest, the Browns have turned to PJ Walker, a more experienced option who started several games for the Panthers last season and has been part of the Cleveland practice squad. Without elite guard Joel Bitonio to provide protection, the 49ers are likely to create separation between the two teams. The Browns’ inability to generate offense against the Ravens led to an uncharacteristically poor tackling performance and an inability to get off the field, which could be detrimental against Christian McCaffrey and the 49ers’ running game.

NFL Pick: George Kittle over 3.5 receptions (+134)

In light of the Browns’ defense, we’ve opted for George Kittle’s receptions total rather than his receiving yards. In his previous outing against the Cowboys, Kittle only required 3 receptions to amass 3 touchdowns and 67 receiving yards. However, he may see even more action this week. QB Brock Purdy will need to make quick passes to evade the Browns’ pass rush, led by the likes of Myles Garrett, who is likely to play despite sustaining an injury in the Ravens game.

Although the Browns boast strong cornerbacks in Denzel Ward, Greg Newsome, and MJ Emerson, their linebackers may be susceptible in coverage. Mark Andrews of the Ravens recorded 5 catches for 80 yards and 2 touchdowns against them. This sets the stage for Kittle to become a frequent target on Sunday.

NFL Pick: Amari Cooper 50+ receiving yards (+132)

This particular leg isn’t a vote of confidence in the Browns’ offense. If anything, it suggests that they may struggle to advance the ball, given their limited options. No team has managed to run successfully against the 49ers this season, and the Browns’ running game has suffered a significant setback following Nick Chubb’s season-ending injury. While Jerome Ford is reportedly recovering from a minor injury early in the week, it’s likely that he, along with Kareem Hunt and Pierre Strong, will find it challenging to make an impact.

In terms of blocking, the Browns fare better in pass protection than run blocking this season. Given the potential of playing from behind for most of the game, it stands to reason that they may focus on feeding the receiver with the best odds of breaking free against a formidable defense. Amari Cooper, who has averaged 64.8 yards per game this year, is the prime candidate. With Walker’s limited practice reps with the first team, it’s plausible that his efforts were concentrated on building chemistry with the team’s primary receiver. Cooper’s standard receiving yardage line sits at just 40.5 with FanDuel. However, increasing it to the alternate line of 50 or more yards elevates our parlay to over 10/1 odds and introduces a contrarian dimension to the spread selection. With the Browns potentially held to under 150 passing yards, Cooper could account for nearly half of that total.

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